Welcome to the Navin laboratory at the MD Anderson Cancer Center.  We are a cancer genomics and computational biology research lab located in the heart of the Texas Medical Center.

Our lab has pioneered the development of
single cell sequencing technologies.  We apply these tools to study complex biological processes that occur in human cancers including transformation, clonal evolution, invasion, metastasis and chemoresistance that are difficult to study in bulk tissues.

Our group is also actively developing novel computational and statistical methods for analyzing large-scale single cell sequencing datasets.  Our primary focus is on breast cancer patients, however we also work with other cancer types.  At MD Anderson we are uniquely positioned to translate our single cell sequencing methods into the clinic, where we expect that they will make a big impact on reducing morbidity and improving the quality of life for patients. 

Single Cell Sequencing

Cancer Genomics

Genome Evolution

Tumor Heterogeneity

Funding Support