Welcome to the Navin laboratory at the MD Anderson Cancer Center.  We are a cancer genomics and computational biology research lab located in the heart of the Texas Medical Center.

Our lab has pioneered the development of
single cell sequencing technologies.  We apply these tools to study complex biological processes in human cancers including transformation, clonal evolution, invasion, metastasis and chemoresistance. 

Our lab also develops novel computational and statistical methods for analyzing large-scale single cell sequencing datasets.  Our work involves many human cancers, but have a major focus on on breast cancer.  At MD Anderson we are uniquely positioned to translate our single cell sequencing methods into the clinic to make an impact on reducing morbidity in cancer patients.  These efforts involve improving early detection, diagnostics, prognostic indexes and guiding therapeutic targeting to improve personalized medicine.

Single Cell Sequencing

Cancer Genomics

Genome Evolution

Tumor Heterogeneity

Funding Support